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Cruises from San Diego
  • Overview
  • Destinations
  • Attractions

Cruises from San Diego

Nicknamed "America's Finest City," and located in Southern California along the Pacific Coast, the metropolitan city of San Diego is well known for its beautiful beaches, resorts, museums, wildlife parks and zoos. Because of its mass appeal, cruises from San Diego are a great option, especially for those that live within driving distance of the city's cruise port.

The cruising season in San Diego is typically from September through May. The cruise lines currently offering cruises from San Diego include Disney Cruise Line, Holland America Line, Royal Caribbean and Norwegian Cruise Line.

Holland America Line offers a large selection of cruises from San Diego. Their premium cruise options include 7-night Mexican Riviera cruises aboard Koningsdam and Zaandam, as well as 17-night and longer Hawaii cruises. Panama Canal cruises are also available aboard a few Holland America ships.

Disney Cruise Line offers the most sailings from San Diego, with 3- to 7-night Baja Mexico cruises aboard Disney Wonder. Royal Caribbean's Serenade of the Seas also features a nice variety of Mexico cruises from San Diego.
Hot San Diego Cruise Deal
Serenade of the Seas Ship: Serenade of the Seas
Itinerary: 7-night Mexico
Date(s): 1/28/2027
Starting at only $450 per person!
ADC's Bonus: Onboard Credit or Pre-Paid Gratuities! Book this Cruise Deal Online
American Discount Cruises & Travel is proud to offer the best deals possible on all cruises from San Diego. Backed by our Backed by our "Low Price Guarantee," and powered by our team of expert travel agents, we're sure to exceed your expectations when booking your next cruise departing from San Diego!


Cruise Lines with Cruises from San Diego

The following cruise lines feature cruises leaving from San Diego. Click the name of the cruise line to view upcoming cruises that they're featuring from San Diego:
Azamara Cruises from San Diego
Azamara Cruises from San Diego
Huge Onboard Credits!
Crystal Cruises from San Diego
Crystal Cruises from San Diego
Huge Onboard Credits on all Crystal Cruises!
Disney Cruises from San Diego
Disney Cruises from San Diego
Special Prices!
Holland America Cruises from San Diego
Holland America Cruises from San Diego
Onboard Credit or Pre-Paid Gratuities!
NCL Cruises from San Diego
NCL Cruises from San Diego
Special Price, Onboard Credit or Pre-Paid Gratuities!
Princess Cruises from San Diego
Princess Cruises from San Diego
Onboard Credit, Cash Back or Pre-Paid Gratuities!
Royal Caribbean Cruises from San Diego
Royal Caribbean Cruises from San Diego
Onboard Credit or Pre-Paid Gratuities!
Silversea Cruises from San Diego
Silversea Cruises from San Diego
Huge Onboard Credits on all Silversea Cruises!


Cruise prices listed above are "from prices," and are in U.S. Dollars (unless noted otherwise), per person, based on double occupancy, including Required Cruise Fees & Expenses, as well as Government Taxes & Fees. Pricing does not include airfare or any other additional charges (unless noted otherwise). Pricing and availability are subject to change at any time prior to successful payment processing and reservation creation. Taxes, fees and port expenses are subject to change even after a reservation has been made, at the discretion of the cruise line. Please click the link provided in the sale box to find out the current pricing and availability. The offer details for any bonuses are listed during the online booking process. Certain restrictions apply.

Destinations for Cruises from San Diego

The following cruise destinations can be visited on a cruise from San Diego. Click any destination to view some of the upcoming cruises from San Diego that are available:
Alaska Cruises from San Diego
Alaska Cruises from San Diego
Caribbean Cruises from San Diego
Caribbean Cruises from San Diego
Europe Cruises from San Diego
Europe Cruises from San Diego
Hawaii Cruises from San Diego
Hawaii Cruises from San Diego
Mexico Cruises from San Diego
Mexico Cruises from San Diego
Pacific Coast Cruises from San Diego
Pacific Coast Cruises from San Diego
Panama Canal Cruises from San Diego
Panama Canal Cruises from San Diego
South America Cruises from San Diego
South America Cruises from San Diego
South Pacific Cruises from San Diego
South Pacific Cruises from San Diego
World Cruises from San Diego
World Cruises from San Diego

Things to do in San Diego

These are just a few of the more popular tourist attractions in San Diego, along with a brief description:

♦ Seaport Village
A car-free shopping and dining district in San Diego, Seaport Village is a great place to consider visiting before or after a cruise leaving from San Diego, California. There are over 70 shops, galleries and eateries in this waterfront-located area. Grab a bite to eat at one of the many bay-view restaurants and then go shopping - you're sure to have a great time! Located nearby this area is the USS Midway, a maritime museum that used to be a naval battleship (from the 1940s to 1990s).

Gaslamp Quarter♦ Gaslamp Quarter
This historic neighborhood is one of the most popular places to visit before or after a cruise from San Diego. This area is home to many festivities throughout the year, including a Mardi Gras celebration and St. Patrick's Day event. There is a nice variety of great restaurants and bars in the Gaslamp Quarter, and PETCO Park (where the San Diego Padres play professional baseball) is only a short walk away. Many people enjoy taking a relaxing walk through this area, checking out the historic buildings (many of which were constructed during the 19th century).

♦ San Diego Zoo
One of the most famous zoos in the world, the San Diego Zoo (located in Balboa Park), is home to over 4,000 animals of more than 800 species. Among the endangered species and rare animals at this zoo are pandas (as this this is one of the few with a giant panda), koalas, polar bears and African black rhinos. This unique zoo is a great place to visit before or after a cruise from San Diego.